Other Ingredients: Cellulose, rice powder, vegetable magnesium stearate and silicon dioxide.
Ray & Terry’s Sleep Potion No. 9 contains 60 vegetarian capsules per bottle.
Suggested Use: Take 2 capsules at bedtime, or as directed by your healthcare professional.
Caution: Sleep Formula Number Nine is not habit-forming or addictive. Use is not recommended for children under 18 or pregnant or nursing mothers. It should not be used by people taking some blood thinners. Please ask your physician before taking this formulation.
L-theanine is an amino acid commonly found in green tea. It has been found to be useful in reducing anxiety and has also been found useful as a sleep aid. The chemical structure of L-theanine is similar to that of the glutamate molecule, one of the brain’s chief calming neurotransmitters. L-theanine also raises levels of other neurotransmitters in the brain such as serotonin, dopamine, GABA and glycine.2
Safety studies have revealed no significant adverse effects on behavior, mortality or morbidity, body weight, blood chemistries or any other problems even in rats fed high doses of this supplement for 13 weeks. L-theanine is a supplement that has been defined as GRAS (generally regarded as safe) by the FDA.3
Bacopa Monnieri, also known as water hyssop, is derived from an herb that is native to northern India and is commonly used in Ayurvedic medicine. It considered one of the most promising naturally-occurring nootropics (“smart drugs”) and has been shown to improve memory and cognitive function. It is often compared to piracetam, a pharmaceutical drug used by some individuals to improve mental ability. Recent studies show bacopa reduces anxiety with properties similar to lorazepam (Xanax), a prescription drug commonly used to reduce anxiety and to promote sleep.4
The active ingredients of ginger are derived from the root of the Zingiber officinale plant. Ginger possesses similarities with turmeric and cardamom. Ginger root is most commonly used as a seasoning and possesses a piquant and spicy flavor. Ginger has found use as a folk remedy in many cultures. Many people drink ginger tea before bed to promote sleep. A recent study showed that Ginger binds to serotonin receptors and as such, potentially could improve mood and reduce anxiety.5 A review of the medical literature has shown that Ginger can benefit patients with nausea and vomiting.6 The US national Library of medicine cautions that people who are taking some prescription blood thinners should avoid ginger supplementation.
GABA (gamma-aminobutyric acid)
Gamma aminobutyric acid (GABA) is a chemical that is naturally found in the brain. It is one of the chief inhibitory neurotransmitters and has been associated with anxiety-reducing, sedative, sleep-promoting and muscle relaxing properties. Drugs of the benzodiazepine family such as alprazolam (Xanax) and diazepam (Valium) act by binding to GABA receptors in the brain.7
- Belelli D, Lambert JJ. Neurosteroids: endogenous regulators of the GABA(A) receptor. Nat Rev Neurosci. 2005 Jul;6(7):565-75.
- Bhattacharya SK, Ghosal S. Anxiolytic activity of a standardized extract of Bacopa monniera: an experimental study. Phytomedicine. 1998 Apr;5(2):77-82.
- Borzelleca JF, Peters D, Hall W. A 13-week dietary toxicity and toxicokinetic study with l-theanine in rats. Food and Chem Toxicol 2006. 44(7):1158–66.
- Giacosa A, Morazzoni P, Bombardelli E, Riva A, Bianchi Porro G, Rondanelli M. Can nausea and vomiting be treated with ginger extract? Eur Rev Med Pharmacol Sci. 2015 Apr;19(7):1291-6.
- LeBlanc M, Mérette C, Savard J, Ivers H, Baillargeon L, Morin CM. Incidence and risk factors of insomnia in a population-based sample. Sleep. 2009 Aug;32(8):1027-37.
- Nathan P, Lu K, Gray M, Oliver, C. The Neuropharmacology of L-Theanine (N-Ethyl-L-Glutamine). J Herbal Pharmacol 2006. 6(2):21–30.
- Riyazi A, Hensel A, Bauer K, Geissler N, Schaaf S, Verspohl EJ. The effect of the volatile oil from ginger rhizomes (Zingiber officinale), its fractions and isolated compounds on the 5-HT3 receptor complex and the serotoninergic system of the rat ileum. Planta Med. 2007 Apr;73(4):355-62.