Other Ingredients: Gelatin, glycerin and purified water.
CAUTION: Do not exceed recommended dose. Pregnant or nursing mothers, children under 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.
WARNING: This product is manufactured and packaged in a facility which may also process milk, soy, wheat, egg, peanuts, tree nuts, fish and crustacean shellfish.
Dosage: (2) - (4) softgels daily, divided and taken with breakfast and with dinner or as directed by your physician.
Ray & Terry‘s CLA 1000 mg contains 120 softgels per bottle.
One study found that participants taking CLA were more likely to avoid seasonal weight gain and fewer of these individuals reported feeling negative emotions during the research period. These findings suggest that CLA can help reduce body fat while supporting a positive mood.8
Ongoing research indicates that CLA helps maintain cellular health and supports proper cell function and division.9,10 Scientists continue to study this nutrient for its effects on human health and there may be additional immune and cardiovascular benefits, including its potential to help support normal blood glucose levels.
As an antioxidant nutrient, CLA is involved with phospholipids in the body. Phospholipids are the major component of cell membranes and the depletion of one such fat, phosphatidylcholine, leads to hardening of cell membranes and is an important part of the aging process.
Animal studies indicate that CLA supports blood vessel health and may help maintain cholesterol levels already within a normal range. Test subjects receiving CLA exhibited healthy levels of triglycerides and LDL, as well as ratios of total cholesterol to HDL.11,12
- Dhiman TR, Anand GR, Satter LD, Pariza MW. Conjugated linoleic acid content of milk from cows fed different diets. J Dairy Sci 1999 Oct;82(10):2146-56.
- Thom E, Wadstein J, Gudmundsen O. (Sep-Oct 2001). "Conjugated linoleic acid reduces body fat in healthy exercising humans". The Journal of International Medical Research 29 (5): 392-396.
- Gaullier JM, Halse J, Høye K, Kristiansen K, Fagertun H, Vik H, Gudmundsen O. "Conjugated linoleic acid supplementation for 1 y reduces body fat mass in healthy overweight humans." Am J Clin Nutr. 2004 Jun;79(6):1118-25.
- Hargrave-Barnes KM, Azain MJ, Miner JL."Conjugated linoleic acid-induced fat loss dependence on Delta6-desaturase or cyclooxygenase." Obesity (Silver Spring). 2008 Oct;16(10):2245-52.
- Whigham LD, Watras AC, and Schoeller DA. "Efficacy of conjugated linoleic acid for reducing fat mass: a meta-analysis in humans." Am. J. Clinical Nutrition. May 2007; 85(5): 1203-11.
- Li JJ, Huang CJ, Xie D."Anti-obesity effects of conjugated linoleic acid, docosahexaenoic acid, and eicosapentaenoic acid." Mol Nutr Food Res. 2008 Jun;52(6):631-45.
- Gaullier JM, Halse J, Høivik HO, Høye K, Syvertsen C, Nurminiemi M, Hassfeld C, Einerhand A, O'Shea M, Gudmundsen O."Six months supplementation with conjugated linoleic acid induces regional-specific fat mass decreases in overweight and obese." Br J Nutr. 2007 Mar;97(3):550-60.
- A C Watras, A C Buchholz, R N Close, Z Zhang and D A Schoeller. "The role of conjugated linoleic acid in reducing body fat and preventing holiday weight gain." Int J Obes. 2007; 31:481-487.
- J Nutr. 2002 Oct;132(10):2995-8. "Inhibition of carcinogenesis by conjugated linoleic acid: potential mechanisms of action." Belury MA.
- Carcinogenesis. 1999 Jun;20(6):1019-24. "Decrease in linoleic acid metabolites as a potential mechanism in cancer risk reduction by conjugated linoleic acid." Banni S, Angioni E, Casu V, Melis MP, Carta G, Corongiu FP, Thompson H, Ip C.
- Tarling EJ, Ryan KJ, Bennett AJ, Salter AM."Effect of dietary conjugated linoleic acid isomers on lipid metabolism in hamsters fed high-carbohydrate and high-fat diets."Br J Nutr. 2008 Nov 5:1-9.
- Nicolosi RJ, Rogers EJ, Kritchevsky D, Scimeca JA, Huth PJ. Dietary conjugated linoleic acid reduces plasma lipoproteins and early aortic atherosclerosis in hypercholesterolemic hamsters. Artery 1997;22(5):266-77.