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Science is quickly developing the technologies needed to radically extend the quality human lifespan. Meanwhile, we need to stay healthy long enough to take advantage of these scientific breakthroughs.
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Vitamin D... is not a vitamin

Monday, October 24, 2011 2:17:09 PM America/New_York

Technically speaking, vitamin D is a pre-hormone. It metabolizes into calcitriol, a substance which can unlock numerous binding sites on the human genome. Deficiency is a factor in diabetes, depression, numerous cancers, heart disease, and more. Research indicates that many health conditions could be improved or avoided with higher vitamin D intake.

The Recommended Daily Allowances (RDAs) for vitamin D have been commonly accepted as too low. Recently (Nov 2010), the official vitamin D recommendations increased.

“Specifically, the Institute of Medicine report advocated a doubling of vitamin D intake for infants (to 400 IU), a tripling of vitamin D intake for those between ages 1 and 50 (to 600 IU), a 50 percent hike in those ages 51 to 70 (to 600 IU), and a 33 percent increase for those older than 71 years old (to 800 IU).” The tolerable upper limit was doubled to 4,000IU.

There are not many foods that contain a good deal of vitamin D and most of the vitamin comes instead from the sun. Dietary sources that we recommend include salmon, mackerel, tuna, and mushrooms. The other dietary sources—fortified milk and cereals—are not recommended by Ray & Terry.

Ray & Terry already recommend 1,000-2,000 IU of vitamin D per day for most people. It’s a good idea to test your blood levels to find your optimal dose: just ask your doctor to run a 25(OH)D test. We advise maintaining 50 ng/dl.

We offer a 1,500 IU Vitamin D3 tablet for less than ten cents a dose. Unless you are getting adequate sun exposure, we recommend taking a look at this simple supplement.
0 Comments | Posted in Specific Vitamins By Eric Huang

What are the benefits of ginseng?

Monday, October 24, 2011 2:13:22 PM America/New_York

Q. What are the benefits of ginseng?

A. Ginseng is a good adaptogenic herb which can help certain people to increase energy and fight stress.

0 Comments | Posted in Specific Vitamins By Eric Huang

Is Knox Gelatin good for joints?

Monday, October 24, 2011 2:10:40 PM America/New_York

Q. Is it beneficial to take something like Knox Gelatin for joints?

A. Anecdotal reports suggest Knox gelatin may help arthritis. In Dr. Grossman's practice, it seems to have limited benefit.

0 Comments | Posted in Specific Vitamins By Eric Huang

Importance of Policosanol source?

Monday, October 24, 2011 2:09:04 PM America/New_York

Q. Does it matter from what material Policosanol comes from ?

A. No, the source of the policosanol does not appear to affect it effectiveness; mostly sugarcane and beeswax are used.

0 Comments | Posted in Specific Vitamins By Eric Huang

How does Prilosec affect absorption?

Monday, October 24, 2011 2:07:38 PM America/New_York

Q. I take 20 mg of Prilosec each morning. Because it's primary effect is to shut down some of the acid produced, are less of the supplements absorbed?

A. Prilosec decreases acid production in the stomach almost to zero. This can lead to malabsorption of nutrients, some minerals in particular. Safer alternatives are preferable when possible. If Prilosec is necessary long-term, some nutrients will not absorb completely, but you will still absorb some.

0 Comments | Posted in Specific Vitamins By Eric Huang

Taking Cholesterol Therapy with Lipitor?

Monday, October 24, 2011 2:06:19 PM America/New_York

Q. I have recently started to take Lipitor. Can I also take Ray & Terry's Cholesterol Therapy?

A. Yes. We recommend that you consult your physician and check your cholesterol periodically. The supplements in Ray & Terry's Cholesterol Therapy improve cholesterol levels using a different mechanism from statin drugs such as Lipitor.

0 Comments | Posted in Specific Vitamins By Eric Huang

COX-2 inhibitors & TDCF?

Monday, October 24, 2011 2:04:13 PM America/New_York

Q. COX-2 inhibitors - With the FDA pulling some drugs that are COX-2 inhibitors, is there any concern over Ray & Terry's Total Joint Care? How is your product different?

A. There is nothing in our Total Joint Care that has any significant COX-2 activity, so there is no concern. Our active ingredients are cetyl myristoleate and glucosamine, which are not COX-2 inhibitors.

0 Comments | Posted in Specific Vitamins By Eric Huang

Vitamin C is too strong for my stomach.

Monday, October 24, 2011 2:02:13 PM America/New_York

Q. Vitamin C - I take Ray & Terry's Total Care Daily Formula and find the vitamin C content is too strong for my stomach. Otherwise, it's the perfect supplement for me. How can I buffer the effects of the C?

A. Unfortunately it is not possible to separate out the vitamin C from the other ingredients and there is no way to "buffer" it. We suggest trying a lower dose (such as 2-3 per day in divided doses).

0 Comments | Posted in Specific Vitamins By Eric Huang

Vitamin E breakdown in TCDF and TEC?

Monday, October 24, 2011 2:00:27 PM America/New_York

Q. What is the breakdown on the 400 IU of Vitamin E found in the Total Care Daily Formula? What about the Total Eye Care?

A. The breakdown per serving is the same for Total Care Daily Formula (6 tablets) and Total Eye Care (4 tablets). Per 400 IU of Vitamin E:

302 IU d-Alpha tocopherol
5 IU d-Beta tocopherol
80 IU d-Gamma tocopherol
13 IU d-Delta tocopherol

0 Comments | Posted in Specific Vitamins By Eric Huang

Is vitamin E still safe?

Monday, October 24, 2011 1:50:33 PM America/New_York

Q. Is vitamin E still safe?

A. Vitamin E is composed of multiple subfractions. Supplementation with alpha-tocopherol alone may reduce blood levels of gamma- and delta-tocopherol. This is important because gamma- and delta-tocopherol are critical to health. As discussed below, Ray & Terry believe that inclusion of mixed tocopherols, found in the Total Care Daily formulation, is safe and healthful.

The following is additional information on this question from our web site: http://www.fantastic-voyage.net/ReaderQandA.htm

Many vitamin E users were upset to read the headline from the November 11, 2004 issue of USA Today -- "Study: High dose of vitamin E may increase death risk." This has led to a storm of controversy about the safety of Vitamin E supplementation. This concern is largely the result of a recent scientific paper by Miller et al entitled "Meta-Analysis: High-dosage vitamin E supplementation may increase all-cause mortality" that was published in the Annals of Internal Medicine."

What the researchers from Johns Hopkins found was that people who took 400 units or more of what they describe as "vitamin E" had a 5% greater risk of premature death than people who took lower doses. Therefore, the researchers concluded "High dosage vitamin E supplements may increase mortality and should be avoided."
There are several flaws with this "meta analysis." According to Steven Milloy of FOXNews.com's "Junk Science," "The researchers didn't study any vitamin E-users first-hand; instead they simply reviewed data from 19 earlier vitamin E clinical trials, including 11 'high dose' trials. But 10 of the 11 'high-dose' trials didn't make any statistically significant correlations between vitamin E use and premature death."

The research in the paper was a meta study, meaning that it combined data from other studies. While results of meta studies can be valid, there are methodological challenges in combining studies that have different control guidelines. The biggest problem with this paper, however, was its confusion of the terms "vitamin E" and "alpha tocopherol." It used these terms interchangeably, and did not take into account that vitamin E is not the same thing as alpha-tocopherol, but contains several other components such as beta-, delta-, and gamma-tocopherol in addition to alpha. Rather, the generic term "vitamin E" was used throughout the paper:

According to Huang and Appel, we know that "Vitamin E is a collective term for eight naturally occurring compounds, four tocopherols (alpha, beta, gamma, and delta) and four tocotrienols (alpha, beta, gamma, and delta)." Yet, by equating alpha-tocopherol with vitamin E, the authors of the meta analysis arrived at seriously flawed conclusions about vitamin E. Their conclusions only apply to alpha-tocopherol.

In addition "these eight forms of vitamin E are not interconvertible in humans." According to Huang and Appel, when people supplement their diets with alpha-tocopherol alone, they reduce their blood levels of gamma- and delta-tocopherol. This is important because gamma- and delta-tocopherol are critical to health. Many researchers now believe that gamma-tocopherol is the most important fraction in vitamin E, contributing to vitamin E's well-known anti-oxidant benefits. In fact, gamma-tocopherol constitutes 70% of the vitamin E consumed in the average American diet.

Therefore, we can draw the following conclusions:

  1. People who take alpha-tocopherol alone may have a slightly increased risk of death. (Five per cent is barely "statistically significant.").
  2. Alpha-tocopherol is not the same thing as vitamin E, as Vitamin E is really composed of multiple subfractions.
  3. Gamma-tocopherol is a critically important form of vitamin E in terms of anti oxidant benefit.
  4. Gamma-tocopherol is the most common dietary form of vitamin E.
  5. Alpha-tocopherol supplementation decreases gamma-tocopherol levels.

Therefore, the primary conclusion that can be drawn from this study is that you might have a slightly increased risk of premature death if you take alpha-tocopherol alone. We recommend, therefore, that you do not take alpha-tocopherol as a stand-alone vitamin E supplement. Instead, you should take a blend which contains all of the vitamin E subfractions.

In Ray Kurzweil and Terry Grossman, M.D.’s book, Fantastic Voyage, Live Long Enough to Live Forever, we recommend that people do not take just alpha tocopherol, but take a vitamin E blend that includes all the tocopherols including gamma tocopherol. The Vitamin E contained in Ray & Terry's Total Daily Care is such a vitamin E blend.

  1. Huang HY and Appel LJ, Supplementation of diets with alpha-tocopherol reduces serum concentrations of gamma- and delta-tocopherol in humans. J Nutr, 2003. 133(10): p. 3137-40.
  2. Devaraj S and Traber MG, ?-Tocopherol, the new vitamin E? Am J Clin Nutr, 2003. 77: p. 530-31.
  3. Wagner KH et al, Gamma-tocopherol--an underestimated vitamin? Ann Nutr Metab, 2004. 48(3): p. 169-88.
0 Comments | Posted in Specific Vitamins By Eric Huang

Is vitamin A safe in large amounts?

Monday, May 9, 2011 11:35:49 PM America/New_York

Q. Vitamin A - I've read that very high doses of vitamin A can result in liver damage.

A. Although vitamin A in high doses may result in liver damage, this does not apply to Beta-Carotene (which is a precursor of vitamin A). That is why we divide the amount in Ray & Terry's Total Care Daily Formula between palmitate and beta carotene. We have recently reformulated this product in light of new and ongoing research on supplements.

0 Comments | Posted in Specific Vitamins By Eric Huang